Core shell nanoparticle applications
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The 3O 4 nanoparticles were further coated with dimercaptosuccinic acid (DMSA) to obtain water dispersity. Vibrating-sample magnetometer shows that the magnetic saturation value of the pristine 3O 4 nanoparticles was measured as 83.3 emu/g. According to the TEM Images, the synthesized nanoparticle size was measured with a total size of 14.9 ± 1.2 nm with core size 9.6 ± 1.1 nm. The 3O 4 core–shell nanoparticles were prepared by thermal decomposition of iron pentacarbonyl and controlled oxidation of iron edge. In this work, we studied the heating characteristics of uniform 3O 4 core–shell nanoparticle under near-infrared laser irradiation and external AC magnetic field applying. Iron oxides as coating materials have attracted much attention due to their low toxicity, good magnetic properties, therapeutic effect and easy synthesis methods. According to improve the stability of iron nanoparticles, the nanoparticles further coated with other material and carbon, silica or other metal oxide are routinely used as candidate materials. As a result, many research works have been made to improve the stability of iron nanoparticles. However, iron itself is easily oxidized under air or water exposure condition. Īmong various nanomaterials that meet the above purpose, iron nanoparticles are characterized by their inherent strong magnetism and material rigidity. In recent years, many kinds of research have been made to prepare magnetic nanoparticles with high magnetic saturation value for more effective heat generation. Unlike gold nanoparticles which possess a mechanical weakness in photothermal process, most of the magnetic nanoparticles do not show obvious morphology changed during magnetic hyperthermia experiments. Therefore, many efforts have been made to prepare new photothermal materials with enhanced mechanical strength. However, the mechanical weakness of gold nanoparticles limited their actual applications in the biomedical field. Regarding hyperthermia treatment, gold nanoparticles are known as the most effective photothermal material due to the surface plasmon phenomenon which enhancing the photothermal effect. Near-infrared laser and external magnetic field which are normally used in this application are known as less harmful to the human body and possess effective cancer cell killing ability. Especially, many kinds of photo and magnetic hyperthermia nanomaterials have been investigated these days. Nanoparticles, such as silica, iron oxide, zinc oxide, and gold nanoparticles, have attracted much research interest for various biomedical applications, for instance, bioimaging, hyperthermia treatment and other therapeutic applications.